Zeranol is a Non-Steroidal Anti-Inflammatory drug. NSAIDsare a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation. Side effects depend on the specific drug, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack and kidney disease. The term nonsteroidal distinguishes these drugs from steroids, which while having a similar eicosanoid-depressing, anti-inflammatory action, have a broad range of other effects.
RIDASCREEN® Zeranol is a competitive enzyme immunoassay for the quantitative analysis of zeranol in urine.
The oestrogenic anabolic agent zeranol (a-Zearalanol) is derived from the mycotoxin zearalenone. It is used to increase the average daily live-weight gain in ruminants and to improve the food conversion efficiency. However, this compound has not been authorized as fattening adjuvant in the EU.
The synthetic compound zeranol possesses about three times the estrogenic activity of zearalenone. Besides its anabolic effects, zeranol causes the clinical signs of hyperestrogenism, particularly reduced fertility and disorders in development. It is thus not impossible that zeranol residues in edible tissues, after use in illegal practice, may lead to a risk for consumers.
- RIDA® Zeranol Spiking Solution
|Test format||Microtiter plate (12 strips with 8 removable wells each)|
|Sample preparation||hydrolysis and chromatographic purification by means of RIDA® C18 columns (Art. Nr. R2002)|
|Incubation time||1 h 15 min|
|Detection limit||1.5 µg/l (ppb)
(the standard range in consideration of the dilution factor is 200 – 16200 ng/l (ppt))(corresponding to the standard substance)
|Cross reactivity||Zeranol: 100 %
Zearalanone: approx. 2 %
ß-Zearalanol: approx. 4 %
Zearalenone: < 0.5 %
α-Zearalenol: approx. 21 %
ß-Zearalenol: approx. 2.5 %
17ß-Estradiol: < 0.02 %
Clenbuterol: < 0.02 %
Testosterone: < 0.02 %
RIDA® Zeranol Spiking Solution
Art. No.: R3399
RIDA® Zeranol Spiking Solution can be used for the production of positive control samples suitable for the validation (e.g. determination of the recovery rate) of the RIDASCREEN® Zeranol test (R3301).
|Test format||zeranol in methanol
concentration: 20 ng/ml